One processor socket in two rack units is an unusual combination, and it is the entire argument for the HPE ProLiant DL345 Gen10 Plus. A single AMD EPYC processor drives sixteen memory slots, up to twenty-six front drive bays and four PCIe slots, and there is no second socket to license against. Storage density is the point.
That matters most where software is licensed per socket or per core. A two-socket server bought for its drive count pays twice for compute it does not need; this platform gives the drive count and the slot count of a 2U chassis on a single-socket licence footprint. Everything about the configuration follows from that trade.
DL345 Gen10 Plus chassis options: four front ends in two rack units
Four chassis types are documented for the DL345 Gen10 Plus: an eight-bay small-form-factor chassis with further small-format or NVMe bay options, a twenty-four-bay small-form-factor chassis with a two-bay rear option taking it to twenty-six drives in total, and eight-bay and twelve-bay large-form-factor chassis supporting SAS and SATA. The twenty-six-drive figure is the headline, and it comes from a rear cage rather than from the front end.
NVMe is handled by enablement kits rather than by chassis type, which is a pattern unique to this platform in the Gen10 Plus line. The sixteen-drive direct-attach kit is P38649-B21 and the twenty-four-drive kit is P38650-B21, and both are conditional: HPE states each can only be selected if an eight-bay NVMe four-lane U.3 or U.2 drive cage is already present. Selecting the U.2 cage narrows the drive list further, because HPE notes that only NVMe U.3 or U.2 drives can then be chosen. Rail kits are chassis-specific, P22018-B21 for small-format and P22019-B21 for large-format builds.
Processors, memory and power on the DL345 Gen10 Plus
The DL345 Gen10 Plus takes one AMD EPYC 7003 processor and carries sixteen DIMM slots across eight channels at two modules per channel. Registered memory reaches 1.0 TB from sixteen 64 GB modules at 3200 MT/s at either one or two modules per channel; load-reduced memory reaches 4.0 TB from sixteen 256 GB modules at 3200 MT/s with one per channel, dropping to 2933 with two.
| Attribute | DL345 Gen10 Plus |
|---|---|
| Form-Factor | 2U rack |
| Sockets | 1 |
| Processor platform | AMD EPYC 7003 |
| Maximum Cores | 64, at the EPYC 7763 and 7713P |
| DIMM Slots | 16, eight channels, two modules per channel |
| Maximum memory | 4.0 TB load-reduced, 1.0 TB registered |
| Front Bays | 8 or 24 SFF, or 8 or 12 LFF; 26 SFF with the rear cage |
| PCIe slots | 4 across primary and secondary risers |
| Storage Controllers | HPE Smart Array, Microchip SmartRAID and MR Tri-Mode families |
| Lifecycle status | RETIRED; QuickSpecs a50002557enw version 34, 2 December 2024 |
Twenty-two processor kits are listed, topped by the EPYC 7763 P38696-B21 at 64 cores, 2.45 GHz and 280 W and the 7713P P38720-B21 at 64 cores and 225 W. Three EPYC 7002 kits also appear - the 7502P P39735-B21, 7302P P39737-B21 and 7232P P39738-B21 - and HPE notes those cannot run two modules per channel at 3200 MT/s. Nine Flex Slot power supplies are offered, the widest range of any single-socket server in this line, from 500 W Platinum 865408-B21 through 1600 W Platinum P38997-B21 and 1600 W direct-current P17023-B21 to the 1800 W to 2200 W Titanium P44712-B21. The 1600 W parts are high-line only and mixing two different supplies is not allowed.
Risers, slots and accelerators on the DL345 Gen10 Plus
Four PCIe 4.0 slots are documented across two risers, and the widths are not uniform. The default primary riser carries slots one and two at sixteen electrical lanes, both full-height full-length. The first secondary riser carries slots three and four at eight electrical lanes in sixteen-lane connectors; an alternative secondary riser gives slot three a full sixteen lanes and drops slot four entirely. That is a genuine either-or: width on one slot, or two slots at half width.
HPE also documents a riser exclusion pair - the slimline primary riser kit P38639-B21 and the x16 secondary riser kits P38641-B21 and P38643-B21 cannot be selected against one another - so a build combining a wide primary with a wide secondary needs checking before it is quoted. The accelerator listed for this platform is the NVIDIA A10 24 GB, R9W59C, and it requires a power cable kit rather than being a card-only fit. Controllers run from the Smart Array E208i-a 804326-B21 and P408i-a 804331-B21 to the 4 GB P816i-a 804338-B21, the Microchip SmartRAID SR932i-p P04220-B21 with 8 GB of wide cache, and the full MR Tri-Mode family. Boot is the NS204i-p P12965-B21.
Where the DL345 Gen10 Plus sits in the ProLiant lifecycle
The DL345 Gen10 Plus is marked RETIRED in HPE's QuickSpecs banner, meaning the base products are no longer available for sale from HPE. The document identifier is a50002557enw, first published on 19 April 2021 and last revised at version 34 on 2 December 2024, with the first-published date verified from the document's own summary-of-changes history.
Thirty-four revisions is the third-highest count in the Gen10 Plus line behind the two mainstream Intel models, and the document froze on the same day as the DL325 Gen10 Plus v2. HPE publishes no support-end date for this platform on any public surface, so none appears here.
DL345 Gen10 Plus vs DL385 Gen10 Plus: one socket or two, in the same chassis class
The DL345 Gen10 Plus and the DL385 Gen10 Plus are both 2U AMD servers with comparable front-end ranges, and the difference between them is the second socket and everything that follows from it. That single difference doubles the memory slots, changes the licensing footprint and changes the drive ceiling.
| Attribute | DL345 Gen10 Plus | DL385 Gen10 Plus |
|---|---|---|
| Sockets | 1 | 2 |
| Processor platform | AMD EPYC 7003, plus three 7002 kits | AMD EPYC 7002 |
| DIMM Slots | 16, eight channels, two per channel | 32, sixteen per processor |
| Maximum memory | 4.0 TB load-reduced, 1.0 TB registered | 8.0 TB load-reduced |
| Front Bays | 8 or 24 SFF, or 8 or 12 LFF | 8 or 24 SFF, or 8 or 12 LFF |
| Maximum drives | 26 SFF with the rear cage | 38 SFF with mid tray and rear cage |
| PCIe slots | 4 | Up to 8, with slots gated by the second processor |
| Lifecycle | RETIRED, doc a50002557enw v34 | RETIRED, doc a00073549enw v31 |
The drive rows are the ones that decide it. Twenty-six against thirty-eight is a real gap, and it exists because the two-socket model supports an eight-bay mid tray that the single-socket model does not. Against that, every slot beyond the fourth on the two-socket machine is gated by its second processor, so a lightly populated DL385 Gen10 Plus does not automatically have more usable expansion than a DL345 Gen10 Plus. Where the single-socket model wins outright is per-socket software licensing.
Choosing within the Gen10 Plus ProLiant line
| Model | Form-Factor | Sockets | DIMM Slots | Maximum drives |
|---|---|---|---|---|
| DL345 Gen10 Plus | 2U rack | 1 | 16 | 26 SFF |
| DL325 Gen10 Plus v2 | 1U rack | 1 | 16 | 10 SFF |
| DL385 Gen10 Plus | 2U rack | 2 | 32 | 38 SFF |
| DL385 Gen10 Plus v2 | 2U rack | 2 | 32 | 36 SFF |
The DL345 Gen10 Plus is the only single-socket 2U server in the AMD Gen10 Plus line, which makes it the one machine in the family with no direct like-for-like alternative. On the Intel side, the live comparisons in our catalogue a generation below are the 2U DL380 Gen10 and the 1U DL360 Gen10, both two-socket platforms.
Buying a refurbished DL345 Gen10 Plus
Three things settle a quote on this platform. The chassis, because a twenty-four-bay machine and an eight-bay machine differ by ordered cages rather than by model number. The NVMe enablement kit, because the direct-attach kits are conditional on a matching drive cage already being present and neither is useful alone. And the secondary riser, because the two variants differ in whether slot four exists at all.
Out-of-band management is HPE Integrated Lights-Out, and its advanced tier is licensed per server against an order rather than travelling with second-hand hardware, so it belongs on the quote as a line item. Enterasource builds each DL345 Gen10 Plus to the specification ordered, testing on receipt, then disassembling, cleaning, inventorying, picking, assembling, configuring and testing again on the bench. Whole systems including this server carry the 2-year Enterasource warranty, and shipping is free to the lower 48 states. Browse the HPE ProLiant server range, or the Dell PowerEdge range for the single-socket AMD alternatives.
Frequently Asked Questions
What are the HPE ProLiant DL345 Gen10 Plus specifications?
One socket for an AMD EPYC 7003 processor to 64 cores, sixteen DIMM slots across eight channels at two modules per channel, a maximum of 4.0 TB with load-reduced modules or 1.0 TB with registered modules, four chassis options covering eight and twenty-four small-format bays and eight and twelve large-format bays, four PCIe 4.0 slots, and Flex Slot power supplies from 500 W to 2200 W.
How many drives does a DL345 Gen10 Plus hold?
Up to twenty-six. The twenty-four-bay small-form-factor chassis takes a two-bay rear drive option for twenty-six drives in total, which is the platform ceiling. The other three front ends are an eight-bay small-format chassis with further small-format or NVMe options, and eight-bay and twelve-bay large-format chassis supporting SAS and SATA drives.
How much memory does the DL345 Gen10 Plus support?
Up to 4.0 TB from sixteen 256 GB load-reduced modules at 3200 MT/s with one module per channel, dropping to 2933 MT/s at two per channel. Registered memory reaches 1.0 TB from sixteen 64 GB modules and holds 3200 MT/s at either population. HPE notes that the three EPYC 7002 kits offered on this platform cannot run two modules per channel at 3200 MT/s.
What is the difference between the DL345 Gen10 Plus and the DL385 Gen10 Plus?
The second socket. The DL345 is single-socket with sixteen memory slots, a 4.0 TB load-reduced ceiling, four PCIe slots and twenty-six drives at most. The DL385 is dual-socket with thirty-two memory slots, an 8.0 TB ceiling, up to eight PCIe slots and thirty-eight drives, but every slot beyond the fourth is gated by its second processor and software licensed per socket costs twice as much.
Where do I find the DL345 Gen10 Plus QuickSpecs, and is the platform still sold?
The document identifier is a50002557enw, first published on 19 April 2021 and last revised at version 34 on 2 December 2024. HPE marks its banner as retired, meaning the base products are no longer available for sale from HPE. Quoting that identifier by name is the reliable way to be given the correct revision rather than a mirrored copy of an older one.
